Herbal Highlight

Cat’s claw is a thick woody vine native to Peru, the Amazon rain forest and other tropical areas of South and Central America. Named for its hooked thorns, which resemble the claws of a cat, it can grow up to 98 feet (30 metres) tall. Cat’s claw has been used in traditional and cultural practices in South America for centuries. Indigenous to Peru, the Ashaninka Indians classified it as a 'powerful plant' and used it to restore health. The Ashaninka’s have used the root bark, and the stem bark as well, for generations. To the priests of this tribe cat’s claw is a sacred plant used to eliminate disturbance in the communication between body and spirit. 

Traditionally cat’s claw has been used in Peru in the form of aqueous or alcoholic infusions as an anti-inflammatory agent for arthritis, gastritis and other disturbances of the gastro-intestinal system, treatment of cancer and for different skin disorders. It is also used for diabetes, asthma, diseases of the urinary tract, wounds, premenstrual syndrome, menstrual irregularity and to recover from childbirth, as a tonic to ward off disease and as an abortifacient. 

A randomised clinical trial assessing the effectiveness of cat’s claw in reducing the adverse effects of chemotherapy concluded that it is an effective adjuvant treatment for breast cancer. Breast cancer is the most frequent tumour affecting women worldwide. Some of the recommended treatments involve chemotherapy which has toxic effects including leukopenia and neutropenia (similar blood conditions that both involve low white blood cell counts). Forty patients with Invasive Ductal Carcinoma-Stage II, who underwent a treatment regimen known as FAC (Fluorouracil, Doxorubicin, Cyclophosphamide), were divided into two groups: the cat’s claw group received chemotherapy plus 300mg of dry cat’s claw extract per day and the cancer group that only received chemotherapy and served as the control experiment. Blood samples were collected before each one of the six chemotherapy cycles and blood counts, immunological parameters, antioxidant enzymes and oxidative stress were analysed. Cat’s claw reduced the neutropenia (not enough neutrophils - a type of white blood cell that play a key role in the body's immune system) caused by chemotherapy and was also able to restore cellular DNA damage. Cat’s claw stimulates the immune system meaning increased resistance to immunosuppression which can be caused by chemotherapy, stress and malnutrition. Unfortunately the cytotoxic action of chemotherapy is not directed just at cancer cells, and so healthy cells are also damaged. This study demonstrates that cat’s claw can potentially strengthen the body’s innate defences and help improve the quality of life for patients overall.

References

Allen L, Buckner A, Buckner CA, Cano P, Lafrenie RM. Uncaria tomentosa (Willd. ex

Schult.) DC (Rubiaceae) Sensitizes THP-1 Cells to Radiation-induced Cell Death.

Pharmacognosy Res. 2017 Jul-Sep;9(3):221-229. doi: 10.4103/pr.pr_83_16.

Farias I, do Carmo Araújo M, Zimmermann ES, Dalmora SL, Benedetti AL, Alvarez-Silva M, et al. Uncaria tomentosa stimulates the proliferation of myeloid progenitor cells. J Ethnopharmacol. 2011 Sep 1;137(1):856-63. doi: 10.1016/j.jep.2011.07.011. Epub 2011 Jul 8.

Keplinger K, Laus G, Wurm M, Dierich MP, Teppner H. Uncaria tomentosa (Willd.) DC.--ethnomedicinal use and new pharmacological, toxicological and botanical results. J Ethnopharmacol. 1999 Jan;64(1):23-34.

Santos Araújo Mdo C, Farias IL, Gutierres J, Dalmora SL, Flores N, Farias J, de Cruz I, Chiesa J, Morsch VM, Chitolina Schetinger MR. Uncaria tomentosa-Adjuvant Treatment for Breast Cancer: Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:676984. doi: 10.1155/2012/676984. Epub 2012 Jun 28. PMID: 22811748; PMCID: PMC3395261.

Happy New Year and a warm welcome to 2025. We have some exciting news to share about a milestone in our journey. This year we are proudly celebrating 140 years of heritage, tradition and dedication to the healing power of nature. For more than a century, over six consecutive generations, the Herbal Extract Company has grown with demand by embracing science while staying true to traditional herbal medicine and family values. From our humble beginnings to becoming a leader in the herbal medicine industry in Australia our story is one of passion, perseverance and unwavering belief in pure plant power.

We may be called the Herbal Extract Company of Australia but we started in Africa in the late 1880s. The Shume family were originally English but in the late 19th Century they emigrated by ship seeking better health. Our company founder Lyndsay Shume’s family settled in Toowoomba in Australia and his great uncle William Shume went to Durban in South Africa. It was there on a farm in 1885 that William’s wife, Henrietta Shume, used blood purifying wild plants foraged from the veld to treat sick animals. When Henrietta found growths in her breast, and operations failed to manage them, she turned to the plants and the growths disappeared. Henrietta went on to manufacture and supply this herbal remedy to chemist shops and subsequently formed the South African Herbal Association. When Lyndsay’s grandfather Henry Shume received letters, and a small herbal remedy book, written by Henrietta he was inspired to pursue herbalism in Australia.

Henry’s son, Archie Shume, carried on the legacy by gathering plants from the Australian bush to treat his own patients. In 1938, just before World War II, Archie's son Lyndsay was born. These were the days when you could not just go and buy herbs from a shop so, as they say, necessity is the mother of invention and Lyndsay began his practical herbal apprenticeship at the age of five picking herbs with his father in the mornings to make herbal medicines. In the 1960s Lyndsay married his wife Helen (nee Smith) and studied by correspondence with the English college National Institute of Medicinal Herbalists (NIMH). Archie died unexpectedly in 1975 and Lyndsay, who was 36 at the time, became overwhelmed with trying to make the herbs for all the hundreds of patients. Lyndsay realised that if he was having difficulties keeping his dispensary full with supplies then his peers were most likely having the same issues. The seed was planted that it would be beneficial to have good quality herbs commercially available for all herbalists. So when the owner of a herbal manufacturing and wholesale business retired in 1988 Lyndsay took the opportunity to realise his dream and bought the business in Sydney. In 1993 we were registered with the Therapeutic Goods Administration and while we had always done sensory testing right from the beginning things then became more technical.

Lyndsay is in his 80s now and the day to day running of the business is with his family including his daughters, Annette and Lyndall, and grandson Matt. Lyndsay has stayed in the herbal business all his life and when we asked him why, he said it’s because he sees people constantly being healed with herbs. From Henrietta's initial discovery to Lyndsay's vision for a reliable source of high-quality herbs, the Herbal Extract Company has grown into a leading provider of liquid herbal medicine.

As we reflect on our rich history we are incredibly grateful for your continued trust and partnership and for sharing our passion for natural health. You have been a vital part of our success and we are more committed than ever to providing you with the highest quality, sustainable and efficacious liquid herbal extracts.

Here's to another year of growth, healing and commitment to wellbeing. We look forward to continuing this journey with you in 2025 and beyond.

New Years’ resolutions have been made and detox season has officially begun for those who ate, drank and were merry. So now it’s time to wake up and smell the dandelion root coffee. The humble dandelion, the bane of lawn owners all over the world, is the herbal ally for people who have been overindulging. Dandelion is highly nutritive, full of minerals and health promoting properties. Through its bitter principles dandelion root stimulates the production of bile and liver function. In the words of New Zealand herbalist Richard Whelan “the liver takes an enormous amount of the brunt of the stress of such lifestyles and, whilst of course they still have to address where they are doing harm, dandelion does a tremendous amount to help knit them back together in the meanwhile.

While occasional detox diets are helpful for a reboot, detoxification is something that is needed to support the body every single day, not just a couple of times each year. The body is equipped with detoxification systems that have been evolving and improving over millions of years and most of these are in the liver. The liver carries over 500 functions in the body and is considered the “master filter,” responsible for processing and filtering the blood in addition to helping detoxify chemicals from the body. When living in an environment where air quality, pollutants and water quality are more of a daily challenge, it is vital to ensure that the liver is functioning optimally. 

Adding a simple, daily liver-supportive herbal formula is an easy way to help promote healthy liver function amidst all of the additional challenges it faces when a healthy lifestyle has slipped by the wayside during the silly season. Herbalists celebrate dandelion as a supreme liver tonic as it excels at clearing excess heat (inflammation), clearing stagnation (congestion) and supporting detoxification of metabolic wastes. A simple alterative tonic recommended by herbalist, midwife and medical doctor Aviva Room combines one quarter of a teaspoon of dandelion root liquid extract in equal parts with burdock (Arctium lappa), globe artichoke (Cynara scolymus), sarsaparilla (Smilax spp.) and ginger (Zingiber officinale). Add these to a glass of sparkling water with lemon and drink 1-2 cups daily for a week, or as a digestive aid after meals.

References

Whelan R. Dandelion. c2011 R.J.Whelan Ltd (accessed 25 Nov 2024). Available

from https://rjwhelan.co.nz/herbs%20A-Z/dandelion.html

Romm A. Top Ten Foods and Herbs to Support Natural Detoxification. (accessed

26 Nov 2024). Available from https://avivaromm.com/detox-every-day/

Love Your Liver Herbal Tincture. The Herbal Academy (updated 11 May

2021;accessed 26 Nov 2024). Available from

https://theherbalacademy.com/blog/liver-tincture/

Cloves are intrinsically linked with Christmas as the heady spice is one of the key ingredients in mulled wine, festive hams and fragrant gingerbread. The powerful clove aroma is particularly associated with the Christmas tradition of making pomanders when oranges are studded with clove buds to make fragrance balls which scent houses and serve as festive decorations. The word clove actually comes from the Latin word clavus, meaning nail, since the shaft and head of the clove bud resembles a nail. 

Old fashioned clove pomanders are perfect for the holiday season. Gathered in bowls around the home, hung in windows with a scarlet ribbon to catch the warmth of the sun, or displayed on the tree, this lovely herbal craft offers a great way to relax and unwind while spending time together with family and friends, or enjoy a little respite time alone amidst the busyness of the season. They are a lovely fragrant gift to share with others to infuse the home with cheer. Cloves are also a key ingredient in the world-famous Worcestershire Sauce and a clove-studded onion can be added to warm milk when making a basic bread sauce. A teaspoon of ground cloves can be mixed into gingerbread dough for an extra spicy kick. 

One of the earliest known spices in trade, cloves are the dried unopened floral buds of an evergreen tree. The quest for cloves is one of those events that have shaped world history. They spurred expeditions and wars, created monopolies, generated fantastic wealth and created great suffering. In medieval Europe, when all spices were scarce, expensive cloves were seen as a sign of indulgence, a show of wealth and a rare prize reserved for special occasions like Christmas. Cloves were considered an internal warming herb which helped dispel cold. They were used as a tonic and stimulant, prescribed as a digestive aid and were a familiar powerful antiseptic. This led to them being used as a breath freshener by dignitaries at the Chinese imperial court during the Han dynasty (200BC). They are still used in toothpastes and gargles today and have been trusted by generations as a first aid remedy for toothache, and to treat inflammation in the mucous membranes of the mouth and throat. They are also given for weak digestion to relieve nausea, vomiting and flatulence. 

References

Hemphill I. There’s More to Cloves than Christmas. Extract from Spice Notes.

c2024 Herbie’s Spices (updated 7 Nov 2024;accessed 25 Nov 2024). Available from

https://www.herbies.com.au/general/theres-more-to-cloves-than-

christmas/?srsltid=AfmBOorrMI_AjIV76cTRxfXgNx_CK8TfAqJdvS7ZliFfaB3PCl_sk

CaB

Justis A. Old-Fashioned Clove Pomanders. The Herbal Academy Holiday Maker’s

Magazine. theherbalacademy.com

Singletary K. Clove. Nutrition Today: July/August 2014;49(4):207-224 doi:

10.1097/NT.0000000000000036

The Christmas tree is the enduring iconic symbol of Christmas. Out of all the Christmas traditions, decorating the Christmas tree with candy canes, tinsel, collected ornaments, baubles and topping it off with a star is certainly up there for some as one of their favourite childhood memories. Adorned with lights, Christmas trees promote hope and offer brightness. There's nothing like the uplifting scent of a real Christmas tree to get you feeling festive. So in the spirit of the season we bring you some of the medicinal attributes of maritime pine.

Maritime pine is famed for its ability to fight inflammation, stimulate immune system action, ease swelling and exert remarkable antioxidant effects. The most extensively studied use of maritime pine is to treat cardiovascular health, especially improvement of endothelial (the inner lining of blood vessels) function and chronic venous insufficiency, a condition defined by poor drainage of blood from veins resulting in swelling or skin problems. Other indications include hypertension, cholesterol reduction, fluid retention, diabetes, diabetic retinopathy, gingival bleeding/plaque, venous leg ulcers. Maritime pine is also included in prescriptions for the common cold, influenza, asthma, bronchitis, sinusitis, upper respiratory catarrh, rheumatism and arthritis. 

A recent study involving 20 children (aged between 8-12) with Attention Deficit Hyperactivity Disorder (ADHD) found that supplementing with maritime pine bark extract significantly decreased inattention, impulsivity and hyperactivity. The randomised, double-blind, crossover, placebo-controlled study included two experimental units (four weeks with maritime pine supplementation and four weeks with placebo supplementation) separated by a two-week washout period. ADHD participants were supplemented with 25mg or 50mg of maritime pine bark extract. The aetiology of ADHD is complicated and includes genetic factors, the abnormal metabolism of neurotransmitters, heavy metal toxicity, food sensitivities, nutritional problems among other risk factors. Recent research shows that oxidative stress may play an important role in the pathology of ADHD and antioxidant supplements have been reported to assist in the treatment of ADHD. Maritime pine bark is abundant in procyanidins, referred to as oligomeric proanthocyanidin complexes (OPCs), a rich source of natural polyphenols. 

References

HEC monograph

Hsu CD, Hsieh LH, Chen YL, Lin IC, Chen YR, Chen CC, Shirakawa H, Yang SC.

Complementary effects of pine bark extract supplementation on inattention,

impulsivity, and antioxidative status in children with attention-deficit hyperactivity

disorder: A double-blinded randomized placebo-controlled cross-over study.

Phytother Res. 2021 Jun;35(6):3226-3235. doi: 10.1002/ptr.7036. Epub 2021 Feb 8.

PMID: 33559134.

The olive tree is one of the oldest cultivated trees on earth. The cultivation of olive started in ancient times and it dates back more than 7000 years. According to archaeological records, olives were commercially cultivated by the Minoans in Crete as far back as 3000 BC. It is the first botanical noted in the Bible, where it is described in Ezekiel 47:12, “The fruit thereof shall be for meat, and the leaf thereof for medicine.” The dove, released from the Ark by Noah in the book of Genesis, returned with an olive branch, thus permanently linking both the olive branch and the dove with peace. The olive branch has transcended its biblical origins to become an international symbol of peace and reconciliation. 

Throughout history there are multiple references for use of olive leaves in the treatment of fevers including intermittent fever, typhoid fever and bilious fever. The leaves were also traditionally used for the treatment of malaria. The first mention of olive leaves’ medicinal use in modern times was in 1843 when Daniel Hanbury of England reported a bitter substance from olive leaf tea was the agent responsible for healing malaria and associated fevers. These findings were reported in 1854 in the Pharmaceutical Journal, along with dosing instructions and a recipe for making the curative tea. In 1898, a strong decoction of olive leaves was cited in King’s American Dispensatory as helpful in regulating body temperature. 

In the last century, extracts of olive leaves have been studied in both animals and humans and have been found to exhibit strong antimicrobial properties against viruses, bacteria, yeast and parasites. Olive leaves also have numerous cardiovascular benefits, some hypoglycaemic activity, and possesses antioxidant activity and can be used for heart health to combat high blood pressure, type 2 diabetes and atherosclerosis. Research suggests the antioxidant action could help support the immune system and general wellbeing by providing protection and repair from oxidative damage to the liver, gastrointestinal tract and nervous system. 

References

Bynum H and W. Remarkable Plants that Shaped our World. Thames and

Hudson:London. 2014. p50

Antoniou C, Hull J. The Anti-cancer Effect of Olea europaea L. Products: a Review.

Curr Nutr Rep. 2021 Mar;10(1):99-124. doi: 10.1007/s13668-021-00350-8. Epub

2021 Mar 8. PMID: 33683579; PMCID: PMC7979598.

Newton J. The Roots of Civilisation. Murdoch Books:Millers Point. 2009. p226-7

de Oliveira NM, Machado J, Chéu MH, Lopes L, Barroso MF, Silva A, Sousa S,

Domingues VF, Grosso C. Potential Therapeutic Properties of Olea europaea

Leaves from Selected Cultivars Based on Their Mineral and Organic Profiles.

Pharmaceuticals. 2024; 17(3):274. https://doi.org/10.3390/ph17030274

Somerville V, Moore R, Braakhuis A. The Effect of Olive Leaf Extract on Upper Respiratory Illness in High School Athletes: A Randomised Control Trial. Nutrients. 2019 Feb 9;11(2):358. doi: 10.3390/nu11020358. PMID: 30744092; PMCID: PMC6412187. vi Hechtman L. Advanced Clinical Naturopathic Medicine. Elsevier:Chatswood. 2020. p716

Chamomile may be small in stature but it is has a huge presence in most herbalist's dispensaries. This familiar plant, with an unmistakable scent and flavour, has a gentle, yet powerful, nature which means it works superbly for both adults and children alike. Well known for its soothing effects, and ability to help people relax and unwind after a long day, chamomile quietens the mind and promotes calm with its nervine sedative qualities. i

As well as being a remarkable relaxant for the nervous system chamomile is also a carminative for the digestion so it shines for digestive problems due to anxiety. It is a mild relaxing nervine with antispasmodic, anti-inflammatory and bitter activity. In the digestive tract chamomile relieves painful digestive spasms and inflammatory digestive complaints such as Crohn’s disease, colitis, irritable bowel disease and irritable bowel syndrome. A 2024 systematic review of clinical trials concluded that oral consumption of chamomile was effective in reducing anxiety in most of the available trials. The researchers said this effect is not limited to diagnosed patients with anxiety disorders and can help relieve anxiety symptoms in different groups for example, the anxiety that women experience during their menstrual cycle, postmenopausal women who show the anxiety symptoms, people suffering from insomnia and anxiety, and patients in the recovery phase of their psychological disorder. ii

There is some evidence to suggest that chamomile may be helpful in managing hyperactive traits of Attention Deficit Hyperactivity Disorder (ADHD). A small study found that children with ADHD who received chamomile extract for four weeks had improvements in hyperactivity and “conduct problems”, compared to a control group. However, the study was small and more research is needed to confirm these findings. iii

References

i Popham S. Chamomile: Beyond the Teabag. The School of Evolutionary

Herbalism. c2014-2024 Available from

https://www.evolutionaryherbalism.com/2022/08/24/chamomile-beyond-the-

teabag/

ii Saadatmand S, Zohroudi F, Tangestani H. The Effect of Oral Chamomile on

Anxiety: A Systematic Review of Clinical Trials. Clin Nutr Res. 2024 Apr

23;13(2):139-147. doi: 10.7762/cnr.2024.13.2.139. PMID: 38784853; PMCID:

PMC11109927.

iii Niederhofer H. Observational study: Matricaria chamomilla may improve some

symptoms of attention-deficit hyperactivity disorder. Phytomedicine. 2009

Apr;16(4):284-6. doi: 10.1016/j.phymed.2008.10.006. Epub 2008 Dec 20. PMID:

19097772.

Korean ginseng’s genus name, Panax, is derived from the Latin panacea meaning “cure all”. Traditional Chinese medicine textbooks describe near-mythical qualities for the human shaped root (the word ginseng is derived from the Chinese word for person) such as restoring balance to one’s life force and increasing longevity. In the East, where it is considered to be the most important of all medicinal herbs, wild mountain ginseng was a revered plant (it is now almost extinct), a treasure beyond price, surrounded by many stories of magical lore. While todays mostly cultivated Korean ginseng is not a miracle herb it is clearly an important remedy with an ancient history of improving health. Herbalists classify Korean ginseng as an adaptogen indicating a wide range of therapeutic uses.

Korean ginseng has shown some potential to help calm symptoms of attention deficit hyperactivity disorder (ADHD). In a study involving 18 children, aged between six and 14 years old who were diagnosed with ADHD, researchers reported improvements in anxiety, personality and social functioning. The children were given 1000mg of Korean ginseng for eight weeks. The effects of Korean ginseng compared to a placebo were evaluated on 70 ADHD patients aged between six and 15 years old. In the intervention group, 33 patients were given 40mL of Korean ginseng twice per day. After eight weeks a decrease in inattention and hyperactivity scores was recorded in the treatment group compared with the control group.

In another study, 40 children with ADHD, aged between six and 12, were given daily supplements containing omega-3 and Korean ginseng. Results of the study suggest that the combination of the two ingredients may help improve memory and attention in children with ADHD

References

i Zhang H, Abid S, Ahn JC, Mathiyalagan R, Kim YJ, Yang DC, Wang Y. Characteristics

of Panax ginseng Cultivars in Korea and China. Molecules. 2020 Jun 5;25(11):2635.

doi: 10.3390/molecules25112635. PMID: 32517049; PMCID: PMC7321059.

ii Hoffmann D. Medical Herbalism. Rochester: Healing Arts Press. 2003. p. 570

iii Lee SH, Park WS, Lim MH. Clinical effects of korean red ginseng on attention

deficit hyperactivity disorder in children: an observational study. J Ginseng Res.

2011 Jun;35(2):226-34. doi: 10.5142/jgr.2011.35.2.226. PMID: 23717065; PMCID:

PMC3659525.

iv Lee J, Lee A, Kim JH, Shin YM, Kim SJ, Cho WD, Lee SI. Effect of Omega-3 and

Korean Red Ginseng on Children with Attention Deficit Hyperactivity Disorder: An

Open-Label Pilot Study. Clin Psychopharmacol Neurosci. 2020 Feb 29;18(1):75-80.

doi: 10.9758/cpn.2020.18.1.75. PMID: 31958908; PMCID: PMC7006981.

v Ko HJ, Kim I, Kim JB, Moon Y, Whang MC, Lee KM, Jung SP. Effects of Korean red

ginseng extract on behavior in children with symptoms of inattention and

hyperactivity/impulsivity: a double-blind randomized placebo-controlled trial. J Child Adolesc Psychopharmacol. 2014 Nov;24(9):501-8. doi: 10.1089/cap.2014.0013. Epub 2014 Nov 4. PMID: 25369174

The vivid crimson stigmas and styles produced by the delicate mauve flowers of the saffron plant have the distinction of being the most expensive food on the planet. The reason is the laborious and labour-intensive method needed to harvest them. Throughout history saffron has been valued for not only infusing dishes in which it is used with a golden glow but also for its medicinal properties. 

A growing body of research suggests that saffron may reduce some of the symptoms, and help improve focus, in people with Attention Deficit Hyperactivity Disorder (ADHD). In 2019, a landmark pilot study brought saffron versus methylphenidate (Ritalin) to the attention of the ADHD community. Researchers found that 20 to 30mg of saffron a day for a period of six weeks was comparable to treatment with methylphenidate for symptoms of both inattention and hyperactivity. 

Since that time, more research has emerged supporting the benefits of saffron for ADHD. A 2022 study found saffron was more effective than methylphenidate for reducing ADHD symptoms of hyperactivity, though methylphenidate was more effective for inattention symptoms. Both therapies improved the number of hours slept among participants, which is a common challenge in ADHD, but only saffron helped with falling asleep. When saffron and methylphenidate were used together in a 2021 clinical trial, the combination was found to be more effective than the use of methylphenidate alone. These findings were supported by a 2022 clinical trial, which also found that saffron and methylphenidate were a superior combination. Despite these promising findings, more large-scale research on saffron for ADHD is needed

References

Newton J. The Roots of Civilisation. Murdoch Books:London. 2009. p.152

Baziar S, Aqamolaei A, Khadem E, Mortazavi SH, Naderi S, Sahebolzamani E, Mortezaei A, Jalilevand S, Mohammadi MR, Shahmirzadi M, Akhondzadeh S. Crocus sativus L. Versus Methylphenidate in Treatment of Children with Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind Pilot Study. J Child Adolesc Psychopharmacol. 2019 Apr;29(3):205-212. doi: 10.1089/cap.2018.0146. Epub 2019 Feb 11. PMID: 30741567.

Blasco-Fontecilla H, Moyano-Ramírez E, Méndez-González O, Rodrigo-Yanguas M, Martin-Moratinos M, Bella-Fernández M. Effectivity of Saffron Extract (Saffr'Activ) on Treatment for Children and Adolescents with Attention Deficit/Hyperactivity Disorder (ADHD): A Clinical Effectivity Study. Nutrients. 2022 Sep 28;14(19):4046. doi: 10.3390/nu14194046. PMID: 36235697; PMCID: PMC9573091.

Khaksarian M, Ahangari N, Masjedi-Arani A, Mirr I, Jafari H, et al. A Comparison of Methylphenidate (MPH) and Combined Methylphenidate with Crocus sativus (Saffron) in the Treatment of Children and Adolescents with ADHD: A Randomized, Double-Blind, Parallel-Group, Clinical Trial. Iran J Psychiatry Behav Sci. 2021;15(3):e108390. https://doi.org/10.5812/ijpbs.108390.

Pazoki B, Zandi N, Assaf Z, Moghaddam HS, Zeinoddini A, Mohammadi MR, Akhondzadeh S Advances in integrative medicine, 2022, 9(1), 37‐43 | added to CENTRAL: 28 February 2022 | 2022 Issue 02 https://doi.org/10.1016/j.aimed.2022.01.002

Reishi is perhaps the most famous of all the medicinal mushrooms. It holds an important place in traditional Chinese medicine, where it is known as lingzhi (spirit plant), for its wide spectrum of actions as an adaptogen, anti-inflammatory, anti-viral and immune modulator. Traditionally it was used in China by Taoist monks to promote a centred calmness, improve meditative practices and attain a long and healthy life. Chinese royalty, seeking longevity, held reishi mushroom in high esteem. 

This versatile mushroom is regarded as a panacea for a wide range of ailments including allergies, asthma, arthritis, bronchitis, hepatitis, autoimmune conditions, heart disease, infections and cancer. It may also help balance hormone levels, decrease anxiety and depression and keep blood sugar levels in check.

Reishi is one of the most popular herbal supplements used by cancer patients around the world. This can be attributed to its potential in alleviating the side effects of chemotherapy, like low immunity and nausea, and enhancing the efficacy of radiotherapy. Although reishi appears to hold some promise for cancer prevention, or treatment, more information is needed to confirm this. A 2020 double-blind randomised controlled trial found preliminary efficacy and safety of reishi and glossy privet (Ligustrum lucidum) in improving the quality of life for patients with non-small cell lung cancer undergoing chemotherapy. 

References

HEC monograph

Liu J, Mao JJ, Li SQ, Lin H. Preliminary Efficacy and Safety of Reishi & Privet ormula on Quality of Life Among Non-Small Cell Lung Cancer Patients Undergoing Chemotherapy: A Randomized Placebo-Controlled Trial. Integr Cancer Ther. 2020 Jan-Dec;19:1534735420944491. doi: 10.1177/1534735420944491. PMID: 32840126; PMCID: PMC7450289.